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A Prospective Study on Local Complications of Primary Total Laryngectomy/Laryngopharyngectomy for Laryngeal and Hypopharyngeal Malignancies

Received: 12 March 2021     Accepted: 27 March 2021     Published: 7 April 2021
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Abstract

Background: Carcinoma larynx is one among the most common head and neck malignancy which accounts for 2% of all cancers whereas hypopharyngeal cancer is one of the most aggressive tumor with poorer prognosis. Total laryngectomy/laryngopharyngectomy (TL/TLP) is the treatment of choice for locally advanced laryngeal and hypopharyngeal cancers. Objectives: To study the complications associated with primary TL/TLP along with the sociodemographic profile and clinicopathologic features of laryngeal and hypopharyngeal cancers. We also aimed to assess the risk factors associated with complications. Methods: All stage III or IVA laryngeal and hypopharyngeal malignancy cases as per American Joint Committee on Cancer (AJCC) 8th edition staging, who underwent primary total laryngectomy/total laryngopharyngectomy during the year 2018-2019 in our institute, KIMS Hubli, have been studied. Sociodemographic profile and clinicopathological features were noted. These patients were followed up for 6 months for any local complications. Results: Mean age of the study population was 58 years with male predominance. Primary glottic carcinoma was most common. Most common presenting symptom was change in voice and most common anatomical site involved was true cords. Overall complication rate was 32%. Most common complication encountered was wound infection and pharyngocutaneous fistula (8% each). As complications set in length of hospital stay increases. We found significant association with PCF and length of hospital stay. Conclusion: With proper case selection, and regular wound care, complications can be avoided in case of TL/TLP. Once complications set in, it increases hospital stay and the expenditure, hence is traumatizing to the patient and hence should be avoided.

Published in International Journal of Clinical Oncology and Cancer Research (Volume 6, Issue 2)
DOI 10.11648/j.ijcocr.20210602.11
Page(s) 49-55
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Laryngectomy, Carcinoma, Larynx, Hypopharynx, Complications

References
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[2] Larbcharoensub N, Wattanatranon D, Leopairut J, Suntisuktana S, Roongpupaht B, Chintrakarn C, Tungkeeratichai J, Praneetvatakul P, Bhongmakapat T, Cheewaruangroj W, Prakunhungsit S. Clinicopathologic Findings and Treatment Outcome of Laryngectomized Patients with Laryngeal Cancer and Hypopharyngeal Cancer: An Experience in Thailand. Asian Pacific Journal of Cancer Prevention: APJCP. 2017; 18 (8): 2035.
[3] Varghese BT, Sebastian P, Mathew A. Treatment outcome in patients undergoing surgery for carcinoma larynx and hypopharynx–a follow-up study. Acta oto-laryngologica. 2009 Jan 1; 129 (12): 1480-5.
[4] Watkinson J, Gilbert R. Stell & Maran's textbook of head and neck surgery and oncology. CRC Press; 2011 Dec 30.
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    Shashidhar Kallappa, Navaneetha Kallidil Kallavalappil. (2021). A Prospective Study on Local Complications of Primary Total Laryngectomy/Laryngopharyngectomy for Laryngeal and Hypopharyngeal Malignancies. International Journal of Clinical Oncology and Cancer Research, 6(2), 49-55. https://doi.org/10.11648/j.ijcocr.20210602.11

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    ACS Style

    Shashidhar Kallappa; Navaneetha Kallidil Kallavalappil. A Prospective Study on Local Complications of Primary Total Laryngectomy/Laryngopharyngectomy for Laryngeal and Hypopharyngeal Malignancies. Int. J. Clin. Oncol. Cancer Res. 2021, 6(2), 49-55. doi: 10.11648/j.ijcocr.20210602.11

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    AMA Style

    Shashidhar Kallappa, Navaneetha Kallidil Kallavalappil. A Prospective Study on Local Complications of Primary Total Laryngectomy/Laryngopharyngectomy for Laryngeal and Hypopharyngeal Malignancies. Int J Clin Oncol Cancer Res. 2021;6(2):49-55. doi: 10.11648/j.ijcocr.20210602.11

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  • @article{10.11648/j.ijcocr.20210602.11,
      author = {Shashidhar Kallappa and Navaneetha Kallidil Kallavalappil},
      title = {A Prospective Study on Local Complications of Primary Total Laryngectomy/Laryngopharyngectomy for Laryngeal and Hypopharyngeal Malignancies},
      journal = {International Journal of Clinical Oncology and Cancer Research},
      volume = {6},
      number = {2},
      pages = {49-55},
      doi = {10.11648/j.ijcocr.20210602.11},
      url = {https://doi.org/10.11648/j.ijcocr.20210602.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20210602.11},
      abstract = {Background: Carcinoma larynx is one among the most common head and neck malignancy which accounts for 2% of all cancers whereas hypopharyngeal cancer is one of the most aggressive tumor with poorer prognosis. Total laryngectomy/laryngopharyngectomy (TL/TLP) is the treatment of choice for locally advanced laryngeal and hypopharyngeal cancers. Objectives: To study the complications associated with primary TL/TLP along with the sociodemographic profile and clinicopathologic features of laryngeal and hypopharyngeal cancers. We also aimed to assess the risk factors associated with complications. Methods: All stage III or IVA laryngeal and hypopharyngeal malignancy cases as per American Joint Committee on Cancer (AJCC) 8th edition staging, who underwent primary total laryngectomy/total laryngopharyngectomy during the year 2018-2019 in our institute, KIMS Hubli, have been studied. Sociodemographic profile and clinicopathological features were noted. These patients were followed up for 6 months for any local complications. Results: Mean age of the study population was 58 years with male predominance. Primary glottic carcinoma was most common. Most common presenting symptom was change in voice and most common anatomical site involved was true cords. Overall complication rate was 32%. Most common complication encountered was wound infection and pharyngocutaneous fistula (8% each). As complications set in length of hospital stay increases. We found significant association with PCF and length of hospital stay. Conclusion: With proper case selection, and regular wound care, complications can be avoided in case of TL/TLP. Once complications set in, it increases hospital stay and the expenditure, hence is traumatizing to the patient and hence should be avoided.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - A Prospective Study on Local Complications of Primary Total Laryngectomy/Laryngopharyngectomy for Laryngeal and Hypopharyngeal Malignancies
    AU  - Shashidhar Kallappa
    AU  - Navaneetha Kallidil Kallavalappil
    Y1  - 2021/04/07
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ijcocr.20210602.11
    DO  - 10.11648/j.ijcocr.20210602.11
    T2  - International Journal of Clinical Oncology and Cancer Research
    JF  - International Journal of Clinical Oncology and Cancer Research
    JO  - International Journal of Clinical Oncology and Cancer Research
    SP  - 49
    EP  - 55
    PB  - Science Publishing Group
    SN  - 2578-9511
    UR  - https://doi.org/10.11648/j.ijcocr.20210602.11
    AB  - Background: Carcinoma larynx is one among the most common head and neck malignancy which accounts for 2% of all cancers whereas hypopharyngeal cancer is one of the most aggressive tumor with poorer prognosis. Total laryngectomy/laryngopharyngectomy (TL/TLP) is the treatment of choice for locally advanced laryngeal and hypopharyngeal cancers. Objectives: To study the complications associated with primary TL/TLP along with the sociodemographic profile and clinicopathologic features of laryngeal and hypopharyngeal cancers. We also aimed to assess the risk factors associated with complications. Methods: All stage III or IVA laryngeal and hypopharyngeal malignancy cases as per American Joint Committee on Cancer (AJCC) 8th edition staging, who underwent primary total laryngectomy/total laryngopharyngectomy during the year 2018-2019 in our institute, KIMS Hubli, have been studied. Sociodemographic profile and clinicopathological features were noted. These patients were followed up for 6 months for any local complications. Results: Mean age of the study population was 58 years with male predominance. Primary glottic carcinoma was most common. Most common presenting symptom was change in voice and most common anatomical site involved was true cords. Overall complication rate was 32%. Most common complication encountered was wound infection and pharyngocutaneous fistula (8% each). As complications set in length of hospital stay increases. We found significant association with PCF and length of hospital stay. Conclusion: With proper case selection, and regular wound care, complications can be avoided in case of TL/TLP. Once complications set in, it increases hospital stay and the expenditure, hence is traumatizing to the patient and hence should be avoided.
    VL  - 6
    IS  - 2
    ER  - 

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Author Information
  • Department of Surgical Oncology, Karnataka Institute of Medical Sciences, Hubli, India

  • Department of Otorhinolaryngology, Karnataka Institute of Medical Sciences, Hubli, India

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