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Clinical and Pathological Features of Small Intestine Tumors

Received: 12 November 2016     Accepted: 17 December 2016     Published: 10 January 2017
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Abstract

Small intestinal tumor is a rare disease, with atypical symptoms, difficult for early diagnosis, with Controversial treatment. This study was to provide reference for prevention, diagnosis and treatment of this tumor. 57 cases of small intestinal tumor were reviewed. Clinicopathological features, survival and prognosis were followed up. Rates were compared using chi-square test, means between multiple groups were compared using ANOVA, OS was analyzed by Kaplan–Meier, COX proportional hazard model was for analyzing the prognosis. Number of cases showed increasing trend since 2000. Female exceeded Male except for jejunum tumor, but without significant difference; There were no significant difference between cases of more and less than 60 years of age. Exept for rare pathological types of carcinoid, female exceeded male, but without significant difference. Abdominal pain was the most common main clinical manifestation. 26.3% patients were found during treatment for intestinal obstruction. Jaundice was the manifestation of duodenal tumors, especially located ampulla of Vater. Anal stopping exhaust defecation was main clinical manifestation of ileal tumors. Main clinical symptom of adenocarcinoma was jaundice. Stromal tumor had clinical manifestations of diarrhea. Abdominal pain was primary clinical manifestation of other extremely rare pathological types. Gastrointestinal endoscopy was the most common examinational procedure. In Conclusions, Adenocarcinoma was the most common type among small intestinal tumors. Age had no effect on the choice of operative or chemotherapy option. Gender or age was independent prognostic factors for OS. Surgery was the most effective treatment, role of chemotherapy displayed no survival benefit.

Published in International Journal of Clinical Oncology and Cancer Research (Volume 1, Issue 1)
DOI 10.11648/j.ijcocr.20160101.13
Page(s) 15-25
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Small Intestinal Tumor, Clinicopathological Features, Treatment, Prognosis

References
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Cite This Article
  • APA Style

    Zheng Wang, Shijie Huang, Jianhua Lin, Yixiong Lin, Jie Zhou. (2017). Clinical and Pathological Features of Small Intestine Tumors. International Journal of Clinical Oncology and Cancer Research, 1(1), 15-25. https://doi.org/10.11648/j.ijcocr.20160101.13

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    ACS Style

    Zheng Wang; Shijie Huang; Jianhua Lin; Yixiong Lin; Jie Zhou. Clinical and Pathological Features of Small Intestine Tumors. Int. J. Clin. Oncol. Cancer Res. 2017, 1(1), 15-25. doi: 10.11648/j.ijcocr.20160101.13

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    AMA Style

    Zheng Wang, Shijie Huang, Jianhua Lin, Yixiong Lin, Jie Zhou. Clinical and Pathological Features of Small Intestine Tumors. Int J Clin Oncol Cancer Res. 2017;1(1):15-25. doi: 10.11648/j.ijcocr.20160101.13

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  • @article{10.11648/j.ijcocr.20160101.13,
      author = {Zheng Wang and Shijie Huang and Jianhua Lin and Yixiong Lin and Jie Zhou},
      title = {Clinical and Pathological Features of Small Intestine Tumors},
      journal = {International Journal of Clinical Oncology and Cancer Research},
      volume = {1},
      number = {1},
      pages = {15-25},
      doi = {10.11648/j.ijcocr.20160101.13},
      url = {https://doi.org/10.11648/j.ijcocr.20160101.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20160101.13},
      abstract = {Small intestinal tumor is a rare disease, with atypical symptoms, difficult for early diagnosis, with Controversial treatment. This study was to provide reference for prevention, diagnosis and treatment of this tumor. 57 cases of small intestinal tumor were reviewed. Clinicopathological features, survival and prognosis were followed up. Rates were compared using chi-square test, means between multiple groups were compared using ANOVA, OS was analyzed by Kaplan–Meier, COX proportional hazard model was for analyzing the prognosis. Number of cases showed increasing trend since 2000. Female exceeded Male except for jejunum tumor, but without significant difference; There were no significant difference between cases of more and less than 60 years of age. Exept for rare pathological types of carcinoid, female exceeded male, but without significant difference. Abdominal pain was the most common main clinical manifestation. 26.3% patients were found during treatment for intestinal obstruction. Jaundice was the manifestation of duodenal tumors, especially located ampulla of Vater. Anal stopping exhaust defecation was main clinical manifestation of ileal tumors. Main clinical symptom of adenocarcinoma was jaundice. Stromal tumor had clinical manifestations of diarrhea. Abdominal pain was primary clinical manifestation of other extremely rare pathological types. Gastrointestinal endoscopy was the most common examinational procedure. In Conclusions, Adenocarcinoma was the most common type among small intestinal tumors. Age had no effect on the choice of operative or chemotherapy option. Gender or age was independent prognostic factors for OS. Surgery was the most effective treatment, role of chemotherapy displayed no survival benefit.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Clinical and Pathological Features of Small Intestine Tumors
    AU  - Zheng Wang
    AU  - Shijie Huang
    AU  - Jianhua Lin
    AU  - Yixiong Lin
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    N1  - https://doi.org/10.11648/j.ijcocr.20160101.13
    DO  - 10.11648/j.ijcocr.20160101.13
    T2  - International Journal of Clinical Oncology and Cancer Research
    JF  - International Journal of Clinical Oncology and Cancer Research
    JO  - International Journal of Clinical Oncology and Cancer Research
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    PB  - Science Publishing Group
    SN  - 2578-9511
    UR  - https://doi.org/10.11648/j.ijcocr.20160101.13
    AB  - Small intestinal tumor is a rare disease, with atypical symptoms, difficult for early diagnosis, with Controversial treatment. This study was to provide reference for prevention, diagnosis and treatment of this tumor. 57 cases of small intestinal tumor were reviewed. Clinicopathological features, survival and prognosis were followed up. Rates were compared using chi-square test, means between multiple groups were compared using ANOVA, OS was analyzed by Kaplan–Meier, COX proportional hazard model was for analyzing the prognosis. Number of cases showed increasing trend since 2000. Female exceeded Male except for jejunum tumor, but without significant difference; There were no significant difference between cases of more and less than 60 years of age. Exept for rare pathological types of carcinoid, female exceeded male, but without significant difference. Abdominal pain was the most common main clinical manifestation. 26.3% patients were found during treatment for intestinal obstruction. Jaundice was the manifestation of duodenal tumors, especially located ampulla of Vater. Anal stopping exhaust defecation was main clinical manifestation of ileal tumors. Main clinical symptom of adenocarcinoma was jaundice. Stromal tumor had clinical manifestations of diarrhea. Abdominal pain was primary clinical manifestation of other extremely rare pathological types. Gastrointestinal endoscopy was the most common examinational procedure. In Conclusions, Adenocarcinoma was the most common type among small intestinal tumors. Age had no effect on the choice of operative or chemotherapy option. Gender or age was independent prognostic factors for OS. Surgery was the most effective treatment, role of chemotherapy displayed no survival benefit.
    VL  - 1
    IS  - 1
    ER  - 

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Author Information
  • Department of General Surgery, Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, China

  • Department of Gastrointestinal Surgery, the 4th Affiliated Hospital of Jinan University, Guangzhou Red Cross Hospital, Guangzhou, China

  • Department of Hepatobiliary Surgery, Nanfang Hospital Affiliated to Southern Medical University, Guangzhou, China

  • Department of Hepatobiliary Surgery, Nanfang Hospital Affiliated to Southern Medical University, Guangzhou, China

  • Department of Hepatobiliary Surgery, Nanfang Hospital Affiliated to Southern Medical University, Guangzhou, China

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